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KMID : 0379120130410040243
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Korean Journal of Mycology
2013 Volume.41 No. 4 p.243 ~ p.247
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Antioxidant and Anti-inflammatory Effects of Phellinus linteus HN1009K
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Kang Hee-Wan
Rhee Man-Hee
Seo Geon-Sik
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Abstract
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Novel Phellinus linteus HN1009K (HK1009) has been characterized on speedy mycelial growth and yearly artificial cultivation. In this study, antioxidant and anti-inflammatory activities of ethanol extract from mycelium and fruiting body of P.linteus HN1009K (HK1009) were compared to those of P. linteus (PL, Korea Sangwhang) and P. baumii (PB, Jangsu Sanghwang) as controls. HK1009 extract showed higher DPPH free radical scavenging activity in both mycelial and fruiting body samples than those of PL and PB. However, in xanthine oxidase assay, antioxidant effect was highly measured on mycelial samples of PL and HK1009. Mycelial extract of HK1009 induced high inhibitory effect on LPS-induced nitric oxide (NO) production in RAW264.7 cells comparing to PL and PB without toxicity on the cells. The results suggest that P. linteus HN1009K possesses superior antioxidant activity and anti-inflammatory effects.
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KEYWORD
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Antioxidant and anti-inflammatory activities, Phellinus linteus HN1009K
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